Son of Antonina Lentini and Giovanni Masnata, he attended elementary school and gymnasium in the Vittorio Emanuele National College of Voghera.
He then associated himself with the second futurism, a more fluid and less rigid movement than futurism born in 1909, where the adherents were not forced into one and only theory, the one that identified with the voice of Filippo Tommaso Marinetti, but were left more free to experiment.
Even if he defines himself a futurist in all respects, Masnata never pushes his contestation to the absolute rejection of the literary tradition because he is convinced that originality should not necessarily be expressed in content but above all in form and thus remains attached to themes such as love, betrayal, the city and nature but also joy for fatherhood, politics and medicine.
Masnata gives his works an unmistakable futuristic imprint especially with regard to the formal aspect. His poetic production includes words free words, words in freedom, aeropoetry and technical poetry, thus following that "polyexpressivity" typical of the movement that leads him to be confirmed with Marinetti of the radio Manifesto, dramatist in screened Souls, free word poet in surgical instruments and in Paroliber tables, theorist and scholar of visuality in visual poetry. He has always been a daring supporter of futurism especially for the configuration itself that the movement offered, with the possibility of conducting new research especially in the field of visuality which made this literary first of all an experimenter of techniques and structures in theater and radio but also in language and syntax of his poems.
1919 is a year of important events: he enrolled in the Faculty of Medicine and Surgery in the University of Pavia where he graduated with honors on November 25, 1925 and met Filippo Tommaso Marinetti and Paolo Buzzi in Corso Venezia 61 in Milan, home of the head of Futurism.